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. 2014:2014:354672.
doi: 10.1155/2014/354672. Epub 2014 Feb 20.

A case of nasal glial heterotopia in an adult

Akira Hagiwara  1 , Noriko Nagai  2 , Yasuo Ogawa  2 , Mamoru Suzuki  2
Affiliations

A case of nasal glial heterotopia in an adult

Akira Hagiwara et al. Case Rep Otolaryngol. 2014.

Abstract

We report a rare case of nasal glial heterotopia in an adult. After the surgery, frontal lobe cerebral hemorrhage developed. A 58-year-old man had unilateral nasal obstruction that progressed for one year. He had been treated for hypertension, chronic heart failure, and cerebral infarction with aspirin and warfarin. A computed tomography scan showed that the tumor occupied the right nasal cavity and the sinuses with small defect in the cribriform plate. The tumor was removed totally with endoscopy. After the operation, the patient developed convulsions and frontal lobe cerebral hemorrhage. The hemorrhage site was located near a defect in the cribriform plate. Nasal glial heterotopia is a rare developmental abnormality, particularly rare in adult. Only few cases were reported. We could not find any report of adult nasal glial heterotopias that developed cerebral hemorrhage as a complication of the surgery.

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Figures

Figure 1
Figure 1
Endoscopic findings of intranasal lesion ※1: Septum ※2: Middle turbinate.
Figure 2
Figure 2
CT showed an isodense mass which occupied the right nasal cavity, maxillary, ethmoid, and frontal sinuses, with no erosion of the bony walls. ↓: A small defect in the cribriform plate.
Figure 3
Figure 3
MRI showed that the tumor had high signal intensity surrounded by an isointense area on the T2-weighted image. No connection was observed with the meninges or cerebral tissue.
Figure 4
Figure 4
(a): glial cells surrounded by the respiratory epithelium with vessels and connective tissue. ※1: respiratory mucosa, ※2: glial cells (b): intense staining of glial elements for glial fibrillary acidic protein (GFAP). ※3: stained cells.
See this image and copyright information in PMC

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