Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2014 Apr 8;11(4):e1001623.
doi: 10.1371/journal.pmed.1001623. eCollection 2014 Apr.

The use of preliminary scientific evidence in public health: a case study of XMRV

Affiliations

The use of preliminary scientific evidence in public health: a case study of XMRV

Kumanan Wilson et al. PLoS Med. .

Abstract

Kumanan Wilson and colleagues explain how the rapid response to XMRV as a novel pathogen has highlighted some challenges pertaining to policy-making and editorial responsibilities. The impact on policy and the propagation of the initial scientific information may not cease if the evidence is disproven and retracted from the peer-reviewed literature, which creates a challenge for regulators and scientific journals. Please see later in the article for the Editors' Summary.

PubMed Disclaimer

Conflict of interest statement

KW is an unpaid member of Canadian Blood Services Scientific Advisory Board. The authors have no other conflicts of interest to report.

Figures

Figure 1
Figure 1. Recommendations for policy makers and journal editors.

References

    1. Kakisi OK, Robinson MJ, Tettmar KI, Tedder RS (2013) The rise and fall of XMRV. Transfus Med 23: 142–151. - PubMed
    1. Erlwein O, Kaye S, McClure MO, Weber J, Wills G, et al. (2010) Failure to detect the novel retrovirus XMRV in chronic fatigue syndrome. PLoS ONE 5: e8519. - PMC - PubMed
    1. van Kuppeveld FJ, van der Meer JW (2012) XMRV and CFS–the sad end of a story. Lancet 379: e27–28. - PubMed
    1. Karafin MS, Stramer SL (2012) The scientific method at work: xenotropic murine leukemia virus-related virus is neither a cause of chronic fatigue syndrome nor a threat to the blood supply. Transfusion 52: 222–225. - PubMed
    1. Dodd RY (2011) Chronic fatigue syndrome, XMRV and blood safety. Future Microbiol 6: 385–389. - PubMed

Publication types

MeSH terms