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Case Reports
. 2014 Apr 10:12:91.
doi: 10.1186/1477-7819-12-91.

Adenoma of the nipple projecting out of the nipple: curative resection without excision of the nipple

Takaaki Fujii  1 , Reina Yajima, Hiroki Morita, Satoru Yamaguchi, Soichi Tsutsumi, Takayuki Asao, Hiroyuki Kuwano
Affiliations
Case Reports

Adenoma of the nipple projecting out of the nipple: curative resection without excision of the nipple

Takaaki Fujii et al. World J Surg Oncol. .

Abstract

Background: Adenoma of the nipple is a rare breast tumor that is often mistaken clinically for Paget's disease and misinterpreted pathologically as invasive ductal carcinoma.

Case report: We report herein a distinctive case of adenoma of the nipple projecting out of the nipple. In the current case, we were able to perform curative resection through a periareolar incision similar to a microdochectomy without excision of the nipple. The diagnosis of adenoma of the nipple was confirmed histopathologically.

Conclusion: Although the tumor was found on top of the nipple, curative tumor resection without excision of the nipple was possible and the nipple was completely preserved. Adenoma of the nipple is a benign tumor, and thus the diagnosis of adenoma of the nipple must be confirmed so that unnecessary surgery can be avoided.

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Figures

Figure 1
Figure 1
Preoperative and postoperative images. (a) Local finding of the left nipple: a red granulation-like tumor on top of the nipple. The mass was soft and fragile and bled easily. (b) The resected specimen contained a solid mass continuing with a projected mass. (c) At the end of the operation: curative excision of the lesion through a periareolar incision under local anesthesia. The mass was resected at a latex duct opening on top of the nipple, similar to a microdochectomy. (d) One month postoperatively.
Figure 2
Figure 2
Mammography, sonography and MRI images. (a) Mammography revealed a well-defined, oval-shaped nodule with uniform density and no microcalcification. (b) Sonography and (c) MRI revealed that the mass under the nipple was continuous with the top of the nipple, showing adenoma of the nipple projecting out of the nipple. MRI, magnetic resonance imaging.
Figure 3
Figure 3
H & E staining and immunohistochemical staining using CD10 and p63. (a) H & E staining revealed papillary proliferation of epithelial cells. (b) Proliferation of glands showed a pseudoinvasive pattern. Immunohistochemical staining using (c) CD10 and (d) p63 was performed to confirm the presence of myoepithelial cells in neoplastic ducts. H & E, hematoxylin and eosin.
See this image and copyright information in PMC

References

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