Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2014 Apr 8;22(4):512-4.
doi: 10.1016/j.str.2014.03.005.

Tracking allosteric propagation with HX-MS

Andrew P Braun  1 , David C Schriemer  2
Affiliations
Free article
Comment

Tracking allosteric propagation with HX-MS

Andrew P Braun et al. Structure. .
Free article

Abstract

The allosterically-induced outcome of nitric oxide (NO) binding to soluble guanylate cyclase (sGC) is well known but poorly understood. As described in this issue of Structure, Underbakke and coworkers apply a powerful hydrogen/deuterium exchange method to follow the key structural elements of the pathway between NO binding and sGC catalytic site activation.

PubMed Disclaimer

Comment on

MeSH terms

LinkOut - more resources