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Review
. 2014 May;55(3):831-3.
doi: 10.3349/ymj.2014.55.3.831. Epub 2014 Apr 1.

Aggravation of hypertriglyceridemia and acute pancreatitis in a bipolar patient treated with quetiapine

Li-Syue Liou  1 , Yi-Jen Hung  2 , Chang-Hsun Hsieh  2 , Fone-Ching Hsiao  2
Affiliations
Review

Aggravation of hypertriglyceridemia and acute pancreatitis in a bipolar patient treated with quetiapine

Li-Syue Liou et al. Yonsei Med J. 2014 May.

Abstract

Pancreatitis is a very rare adverse effect of quetiapine treatment, with only 5 cases of quetiapine-associated pancreatitis reported in the English literature to date. Herein, we report one patient who developed severe hypertriglyceridemia (>1000 mg/dL) after quetiapine administration, resulting in acute pancreatitis. An analysis of the underlying pathogenic mechanisms and a review of relevant literature are also presented. Clinicians should be aware of the potentially life-threatening metabolic disturbances and/or pancreatitis associated with quetiapine therapy.

Keywords: Quetiapine; hypertriglyceridemia; pancreatitis.

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Conflict of interest statement

The authors have no financial conflicts of interest.

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