Everything old is new again: (linc)RNAs make proteins!
- PMID: 24719208
- PMCID: PMC4193927
- DOI: 10.1002/embj.201488303
Everything old is new again: (linc)RNAs make proteins!
Abstract
Long non-coding RNAs have become the focus of considerable interest over the past few years. Intriguing novel functions have been reported for lincRNAs. Three recent papers identify lincRNAs that work in a more conventional way-encoding protein-in each case a small polypeptide with an interesting biological activity (Magny et al, 2013; Pauli et al, 2014), (Bazzini et al, 2014).
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Identification of small ORFs in vertebrates using ribosome footprinting and evolutionary conservation.EMBO J. 2014 May 2;33(9):981-93. doi: 10.1002/embj.201488411. Epub 2014 Apr 4. EMBO J. 2014. PMID: 24705786 Free PMC article.
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