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Comment
. 2014 May 2;33(9):937-8.
doi: 10.1002/embj.201488303. Epub 2014 Apr 9.

Everything old is new again: (linc)RNAs make proteins!

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Comment

Everything old is new again: (linc)RNAs make proteins!

Stephen M Cohen. EMBO J. .

Abstract

Long non-coding RNAs have become the focus of considerable interest over the past few years. Intriguing novel functions have been reported for lincRNAs. Three recent papers identify lincRNAs that work in a more conventional way-encoding protein-in each case a small polypeptide with an interesting biological activity (Magny et al, 2013; Pauli et al, 2014), (Bazzini et al, 2014).

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Figures

Figure 1
Figure 1. lincRNAs have been thought to act as non-coding molecules
Recent studies identified several lincRNAs that, unexpectedly, encode for small polypeptides.

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