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. 2014 Jan;16(1):e14643.
doi: 10.5812/ircmj.14643. Epub 2014 Jan 5.

The Effect of Rosa Damascena Extract on Primary Dysmenorrhea: A Double-blind Cross-over Clinical Trial

Soheila Bani  1 , Shirin Hasanpour  1 , Zeinabalsadat Mousavi  1 , Parvin Mostafa Garehbaghi  2 , Morteza Gojazadeh  3
Affiliations

The Effect of Rosa Damascena Extract on Primary Dysmenorrhea: A Double-blind Cross-over Clinical Trial

Soheila Bani et al. Iran Red Crescent Med J. 2014 Jan.

Abstract

Background: Dysmenorrhea is one of the most common types of cyclic pain that affects 50% of women and girls in their menstrual ages. Because of the side-effects and contraindications of chemical medicines, using herbs has been investigated in treating dysmenorrhea.

Objectives: The aim of this study was to determine the effect of Rosa damascena extract on primary dysmenorrhea among the students of Kowsar dormitory in Tabriz University of Medical Sciences.

Materials and methods: This study was performed in Iran on 92 single 18-24 year old students with BMI :19-25 and obtaining pain intensity score of 5-8 in Visual Analogue Scale that were randomly classified and included in two groups of 46 persons. The participants received two capsules of Mefenamic Acid and Rosa damascena with the similar physical properties in two consecutive cycles per 6 hours for 3 days in a cross-over form. The data were collected through the questionnaire of demographic characteristics and check-list of visual analogue scale. Descriptive statistics and repeated measurement test and independent samples t test by using SPSS (13/win) were used in order to determine and compare the effects of two drugs on dysmenorrheal pain intensity of the groups.

Results: There was a significant difference between the average of pain intensity at different hours of measurement in each group after the end of first cycle and second cycle (P < 0.001). There was no significant difference between the average of pain intensity in two groups in the first cycle (P = 0.35) and second cycle (P = 0.22).

Conclusions: In this study¸ Rosa damascena and Mefenamic acid had similar effects on pain intensity of primary dysmenorrhea . With further studies, Rosa damascena which has no chemical side effects¸ can be suggested for treating primary dysmenorrhea.

Keywords: Dysmenorrhea; Mefenamic Acid; Rosa.

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Figures

Figure 1.
Figure 1.. The comparison of Pain Scores in Different Hours of Evaluation After the End of First Cycle in Two Groups
Figure 2.
Figure 2.. The Comparison of Pain Scores in Different Hours of Evaluation After the End of Second Cycle in Two Groups
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