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. 2014 Jul;32(6):605-9.
doi: 10.1016/j.mri.2014.03.009. Epub 2014 Mar 15.

MR evaluation of breast lesions obtained by diffusion-weighted imaging with background body signal suppression (DWIBS) and correlations with histological findings

Marco Moschetta  1 , Michele Telegrafo  2 , Leonarda Rella  2 , Arcangela Capolongo  2 , Amato Antonio Stabile Ianora  2 , Giuseppe Angelelli  2
Affiliations

MR evaluation of breast lesions obtained by diffusion-weighted imaging with background body signal suppression (DWIBS) and correlations with histological findings

Marco Moschetta et al. Magn Reson Imaging. 2014 Jul.

Abstract

Objectives: Diffusion imaging represents a new imaging tool for the diagnosis of breast cancer. This study aims to investigate the role of diffusion-weighted MRI with background body signal suppression (DWIBS) for evaluating breast lesions.

Methods: 90 patients were prospectively evaluated by MRI with STIR, TSE-T2, contrast enhanced THRIVE-T1 and DWIBS sequences. DWIBS were analyzed searching for the presence of breast lesions and calculating the ADC value. ADC values of ≤1.44×10(-3)mm(2)/s were considered suspicious for malignancy. This analysis was then compared with the histological findings. Sensitivity, specificity, diagnostic accuracy (DA), positive predictive value (PPV) and negative (NPV) were calculated.

Results: In 53/90 (59%) patients, DWIBS indicated the presence of breast lesions, 16 (30%) with ADC values of >1.44 and 37 (70%) with ADC≤1.44. The comparison with histology showed 25 malignant and 28 benign lesions. DWIBS sequences obtained sensitivity, specificity, DA, PPV and NPV values of 100, 82, 87, 68 and 100%, respectively.

Conclusion: DWIBS can be proposed in the MRI breast protocol representing an accurate diagnostic complement.

Keywords: Breast; DWIBS; Diffusion; MRI; Magnetic resonance.

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