Comment on

• Unified polymerization mechanism for the assembly of ASC-dependent inflammasomes.

  Lu A, Magupalli VG, Ruan J, Yin Q, Atianand MK, Vos MR, Schröder GF, Fitzgerald KA, Wu H, Egelman EH. Lu A, et al. Cell. 2014 Mar 13;156(6):1193-1206. doi: 10.1016/j.cell.2014.02.008. Cell. 2014. PMID: 24630722 Free PMC article.
• Prion-like polymerization underlies signal transduction in antiviral immune defense and inflammasome activation.

  Cai X, Chen J, Xu H, Liu S, Jiang QX, Halfmann R, Chen ZJ. Cai X, et al. Cell. 2014 Mar 13;156(6):1207-1222. doi: 10.1016/j.cell.2014.01.063. Cell. 2014. PMID: 24630723 Free PMC article.