Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2014 Mar 2:2014:969876.
doi: 10.1155/2014/969876. eCollection 2014.

Carbonate hydroxyapatite and silicon-substituted carbonate hydroxyapatite: synthesis, mechanical properties, and solubility evaluations

L T Bang  1 , B D Long  2 , R Othman  1
Affiliations

Carbonate hydroxyapatite and silicon-substituted carbonate hydroxyapatite: synthesis, mechanical properties, and solubility evaluations

L T Bang et al. ScientificWorldJournal. .

Abstract

The present study investigates the chemical composition, solubility, and physical and mechanical properties of carbonate hydroxyapatite (CO3Ap) and silicon-substituted carbonate hydroxyapatite (Si-CO3Ap) which have been prepared by a simple precipitation method. X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), X-ray fluorescence (XRF) spectroscopy, and inductively coupled plasma (ICP) techniques were used to characterize the formation of CO3Ap and Si-CO3Ap. The results revealed that the silicate (SiO4(4-)) and carbonate (CO3(2-)) ions competed to occupy the phosphate (PO4(3-)) site and also entered simultaneously into the hydroxyapatite structure. The Si-substituted CO3Ap reduced the powder crystallinity and promoted ion release which resulted in a better solubility compared to that of Si-free CO3Ap. The mean particle size of Si-CO3Ap was much finer than that of CO3Ap. At 750°C heat-treatment temperature, the diametral tensile strengths (DTS) of Si-CO3Ap and CO3Ap were about 10.8 ± 0.3 and 11.8 ± 0.4 MPa, respectively.

PubMed Disclaimer

Figures

Figure 1
Figure 1
XRD patterns of the as-prepared powders: (a) CO3Ap and (b) Si-CO3Ap.
Figure 2
Figure 2
XRD patterns of the samples after heat-treatment of Si-CO3Ap at (a) 650°C, (b) 700°C, and (c) 750°C and of CO3Ap at (d) 650°C, (e) 700°C, and (f) 750°C.
Figure 3
Figure 3
FTIR spectra of the as-prepared powders: (a) CO3Ap and (b) Si-CO3Ap.
Figure 4
Figure 4
Density of samples after heat-treatment at different temperatures. *P < 0.05 and # P < 0.05, statistically different compared to CO3Ap and Si-CO3Ap heat-treated at 650°C, respectively; n = 8.
Figure 5
Figure 5
Diametral tensile strength (DTS) of samples at different temperatures. *P < 0.05 and # P < 0.05, statistically different compared to CO3Ap and Si-CO3Ap heat-treated at 650°C, respectively; n = 8.
Figure 6
Figure 6
DTS versus heat-treatment temperatures for various carbonate hydroxyapatites.
Figure 7
Figure 7
Released ions and pH of SBF solution after immersion: (a) released Ca, (b) released Si, and (c) pH.
See this image and copyright information in PMC

References

    1. Dorozhkin SV. Nanosized and nanocrystalline calcium orthophosphates. Acta Biomaterialia. 2010;6(3):715–734. - PubMed
    1. Wagoner Johnson AJ, Herschler BA. A review of the mechanical behavior of CaP and CaP/polymer composites for applications in bone replacement and repair. Acta Biomaterialia. 2011;7(1):16–30. - PubMed
    1. Gomes S, Nedelec J-M, Jallot E, Sheptyakov D, Renaudin G. Silicon location in silicate-substituted calcium phosphate ceramics determined by neutron diffraction. Crystal Growth and Design. 2011;11(9):4017–4026.
    1. Kolmas J, Jaklewicz A, Zima A, et al. Incorporation of carbonate and magnesium ions into synthetic hydroxyapatite: the effect on physicochemical properties. Journal of Molecular Structure. 2011;987(1–3):40–50.
    1. Lombardi M, Palmero P, Haberko K, Pyda W, Montanaro L. Processing of a natural hydroxyapatite powder: from powder optimization to porous bodies development. Journal of the European Ceramic Society. 2011;31(14):2513–2518.

Publication types

MeSH terms