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Review
. 2014 May;41(2):299-313.
doi: 10.1016/j.ucl.2014.01.011.

Optimization of prostate biopsy: review of technique and complications

Marc A Bjurlin  1 , James S Wysock  1 , Samir S Taneja  2
Affiliations
Review

Optimization of prostate biopsy: review of technique and complications

Marc A Bjurlin et al. Urol Clin North Am. 2014 May.

Abstract

A 12-core systematic biopsy that incorporates apical and far-lateral cores in the template distribution allows maximal cancer detection and avoidance of a repeat biopsy while minimizing the detection of insignificant prostate cancers. Magnetic resonance imaging-guided prostate biopsy has an evolving role in both initial and repeat prostate biopsy strategies, potentially improving sampling efficiency, increasing the detection of clinically significant cancers, and reducing the detection of insignificant cancers. Hematuria, hematospermia, and rectal bleeding are common complications of prostate needle biopsy, but are generally self-limiting and well tolerated. All men should receive antimicrobial prophylaxis before biopsy.

Keywords: Biopsy core number; Magnetic resonance imaging; Prostate needle biopsy; Quinolone-reistant infection.

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Figures

Fig. 1
Fig. 1
End-fire (A) and side-fire (B) configurations of the transrectal ultrasound biopsy probe.
Fig. 2
Fig. 2
Artemis 3D imaging and navigation system. Courtesy of Eigen, Grass Valley, CA; with permission.
Fig. 3
Fig. 3
MRI-guided repeat prostate biopsy after a negative 12-core template biopsy. MRI demonstrated a left anterior mid-to-apex transition zone lesion that appeared to intimately involve anterior fibromuscular stroma (suspicion score 4/5) on T2 weighed imaging (A) and apparent diffusion coefficient map (B). Targeted biopsy revealed Gleason score 3+4=7 prostate cancer in 2 of 2 cores, 20–70% of each core.
See this image and copyright information in PMC

References

    1. Taneja SSBM, Carter HB, Schellhammer P, Cookson MS, Gomella LG, Troyer D, Wheeler TM, Schlossberg S, Penson DF. White Paper: AUA/Optimal Techniques of Prostate Biopsy and Specimen Handling. 2013 http://www.auanet.org/common/pdf/education/clinicalguidance/Prostate-Bio.... - PMC - PubMed
    1. Bjurlin MA, Carter HB, Schellhammer P, Cookson MS, Gomella LG, Troyer D, Wheeler TM, Schlossberg S, Penson DF, Taneja SS. Optimization of initial prostate biopsy in clinical practice: sampling, labeling and specimen processing. J Urol. 2013;189:2039–46. - PMC - PubMed
    1. Babaian RJ, Toi A, Kamoi K, Troncoso P, Sweet J, Evans R, Johnston D, Chen M. A comparative analysis of sextant and an extended 11-core multisite directed biopsy strategy. J Urol. 2000;163:152–7. - PubMed
    1. Guichard G, Larre S, Gallina A, Lazar A, Faucon H, Chemama S, Allory Y, Patard JJ, Vordos D, Hoznek A, et al. Extended 21-sample needle biopsy protocol for diagnosis of prostate cancer in 1000 consecutive patients. Eur Urol. 2007;52:430–5. - PubMed
    1. de la Taille A, Antiphon P, Salomon L, Cherfan M, Porcher R, Hoznek A, Saint F, Vordos D, Cicco A, Yiou R, et al. Prospective evaluation of a 21-sample needle biopsy procedure designed to improve the prostate cancer detection rate. Urology. 2003;61:1181–6. - PubMed

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