ERQC autophagy: Yet another way to die
- PMID: 24725593
- DOI: 10.1016/j.molcel.2014.03.037
ERQC autophagy: Yet another way to die
Abstract
A novel autophagy pathway eliminates nonnative polytopic membrane proteins from the endoplasmic reticulum that evade degradation by the ubiquitin proteasome system.
Copyright © 2014 Elsevier Inc. All rights reserved.
Comment on
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Protein quality control in the cytosol and the endoplasmic reticulum: brothers in arms.Mol Cell. 2010 Oct 22;40(2):238-52. doi: 10.1016/j.molcel.2010.10.001. Mol Cell. 2010. PMID: 20965419 Review.
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Quality control autophagy degrades soluble ERAD-resistant conformers of the misfolded membrane protein GnRHR.Mol Cell. 2014 Apr 10;54(1):166-179. doi: 10.1016/j.molcel.2014.02.025. Epub 2014 Mar 27. Mol Cell. 2014. PMID: 24685158 Free PMC article.
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