Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2014 Apr 13:14:48.
doi: 10.1186/1471-2415-14-48.

Unilateral morning glory optic disc anomaly in a case with Down syndrome

Ahmet Altun  1 , Gulengul Altun, Sevda Aydin Kurna, Osman Okan Olcaysu, Suat Fazil Aki
Affiliations
Case Reports

Unilateral morning glory optic disc anomaly in a case with Down syndrome

Ahmet Altun et al. BMC Ophthalmol. .

Abstract

Background: This case is unique because it is the first reported case of Down syndrome with morning glory optic disc anomaly in literature.

Case presentation: A 15-year-old girl with features of Down syndrome presented to the Clinic of Ophthalmology for a regular ophthalmologic examination. Her best corrected visual acuity was 20/50 in the right eye and 20/20 in the left eye. The fundus examination revealed findings compatible with unilateral morning glory optic disc anomaly in the right eye. The patient underwent a complete ophthalmologic and systemic evaluation to explore possible associated findings.

Conclusion: This case report emphasizes the importance of ophthalmic screening-examinations in Down children to rule out any vision relevant pathology.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Picture of the case with the characteristic face of Down syndrome.
Figure 2
Figure 2
Fundus photographs of the right eye (A) and the left eye (B).
Figure 3
Figure 3
Conoid excavation in the posterior pole with the optic disc in the right eye.
Figure 4
Figure 4
Retinal nerve fiber layer was reduced in the right eye (A) and within the normal limits in the left eye (B).
Figure 5
Figure 5
Axial optical coherence tomography scan of macula of the right eye (A) and the left eye (B).
Figure 6
Figure 6
Coronal and sagittal optical coherence tomography scan of the optic nerve head of the right eye (A) and the left eye (B).
Figure 7
Figure 7
Late phase of the fundus fluorescein angiography of the right eye (A) and the left eye (B).
See this image and copyright information in PMC

References

    1. Down JL. Observations on an ethnic classification of idiots. Ment Retard. 1995;33(1):54–56. - PubMed
    1. Improved national prevalence estimates for 18 selected major birth defects--United States, 1999-2001. MMWR Morb Mortal Wkly Rep. 2006;54(51):1301–1305. - PubMed
    1. Creavin AL, Brown RD. Ophthalmic abnormalities in children with Down syndrome. J Pediatr Ophthalmol Strabismus. 2009;46:76–82. doi: 10.3928/01913913-20090301-06. - DOI - PubMed
    1. Davis JS. Ocular manifestations in Down syndrome. Pa Med. 1996;99(suppl):67–70. - PubMed
    1. Kindler P. Morning glory syndrome: unusual congenital optic disk anomaly. Am J Ophthalmol. 1970;69:376–384. - PubMed

Publication types