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. 2014;38(3-4):161-9.
doi: 10.1159/000358051. Epub 2014 Apr 8.

Long-term mortality in a cohort of home-dwelling elderly with mild Alzheimer's disease and Lewy body dementia

Ragnhild Oesterhus  1 , Hogne Soennesyn, Arvid Rongve, Clive Ballard, Dag Aarsland, Corinna Vossius
Affiliations

Long-term mortality in a cohort of home-dwelling elderly with mild Alzheimer's disease and Lewy body dementia

Ragnhild Oesterhus et al. Dement Geriatr Cogn Disord. 2014.

Abstract

Objective: To study mortality in subjects with mild dementia in Norway with a special focus on patients with Lewy body dementia (LBD) compared to Alzheimer's disease (AD).

Methods: All referrals of mild dementia patients to dementia clinics in western Norway from March 2005 to March 2007 were included and followed until December 2012. Diagnoses were based on a comprehensive standardized assessment program.

Results: Of 209 patients, 137 (66%) had AD and 53 (25%) had LBD. Dementia was associated with increased mortality (standardized mortality ratio = 1.8, AD 1.5, LBD 2.6). The median survival time was 6.2 years (95% CI 5.4-6.9). Predictors of mortality were age at diagnosis (HR 1.1 per year) and LBD diagnosis (HR 2.4).

Conclusion: Dementia patients had an increased mortality, particularly those with LBD.

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