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Comment
. 2014 May;11(5):245-6.
doi: 10.1038/nrclinonc.2014.65. Epub 2014 Apr 15.

Melanoma: Why is sentinel lymph node biopsy 'standard of care' for melanoma?

James C Yang  1 , Richard M Sherry  1 , Steven A Rosenberg  1
Affiliations
Comment

Melanoma: Why is sentinel lymph node biopsy 'standard of care' for melanoma?

James C Yang et al. Nat Rev Clin Oncol. 2014 May.

Abstract

A large definitive trial comparing the use of sentinel lymph node biopsy and elective lymph node dissection to observation in patients with intermediate thickness melanomas fails to show improved melanoma-specific survival. These results demand reconsideration of the routine use of sentinel lymph node biopsy in the treatment of primary melanoma.

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Conflict of interest statement

Competing interests

The authors declare no competing interests.

Comment in

Comment on

  • Final trial report of sentinel-node biopsy versus nodal observation in melanoma.
    Morton DL, Thompson JF, Cochran AJ, Mozzillo N, Nieweg OE, Roses DF, Hoekstra HJ, Karakousis CP, Puleo CA, Coventry BJ, Kashani-Sabet M, Smithers BM, Paul E, Kraybill WG, McKinnon JG, Wang HJ, Elashoff R, Faries MB; MSLT Group. Morton DL, et al. N Engl J Med. 2014 Feb 13;370(7):599-609. doi: 10.1056/NEJMoa1310460. N Engl J Med. 2014. PMID: 24521106 Free PMC article. Clinical Trial.

References

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