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Comment
. 2014 Apr 14;24(8):R317-9.
doi: 10.1016/j.cub.2014.02.051.

Protein translocation: the Sec61/SecYEG translocon caught in the act

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Protein translocation: the Sec61/SecYEG translocon caught in the act

Martin Spiess. Curr Biol. .
Free article

Abstract

The Sec61/SecYEG complex mediates both the translocation of newly synthesized proteins across the membrane and the integration of transmembrane segments into the lipid bilayer. New cryo-electron microscopy studies show ribosome-channel complexes in action and reveal their repertoire of conformational states.

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