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Comment
. 2014 Aug;137(Pt 8):e292.
doi: 10.1093/brain/awu073. Epub 2014 Apr 15.

Congenital mirror movements: lack of decussation of pyramids

Pedro Brandão  1 , Cassio Jovem  2 , Joaquim Pereira Brasil-Neto  3 , Carlos Tomaz  3 , Maxime Descoteaux  4 , Nasser Allam  5
Affiliations
Comment

Congenital mirror movements: lack of decussation of pyramids

Pedro Brandão et al. Brain. 2014 Aug.
No abstract available

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Figures

Figure 1
Figure 1
Synkinetic contralateral movements (mirror movements) with distal motor task of the upper limb: (A and B) voluntary hand grip of the right hand, (C–F) intentional alternating finger tapping of the left hand, using from second to fifth hand digits.
Figure 2
Figure 2
Bilateral functional MRI blood oxygen level-dependent response over precentral, post central gyrus and supplementary motor area during unimanual task. The patient was asked to perform a finger tapping task with either (A) the right hand or (B) the left hand.
Figure 3
Figure 3
3.0 T MRI DTI tractography, (A) missing decussation of pyramids, with strictly unilateral non-crossing corticospinal tracts, and (B) a control subject, with normal crossing corticospinal tracts.
Figure 4
Figure 4
HARDI/Q-ball fibre tracking through orientation distribution function estimation of the corticospinal projection of the patient with congenital mirror movements. Strictly non-crossed corticospinal tract is shown in (A and B). A crossed corticospinal fibre bundle is not found when the region of interest is segmented to the contralateral lateral funiculus in (C).
See this image and copyright information in PMC

Comment in

Comment on

  • RAD51 deficiency disrupts the corticospinal lateralization of motor control.
    Gallea C, Popa T, Hubsch C, Valabregue R, Brochard V, Kundu P, Schmitt B, Bardinet E, Bertasi E, Flamand-Roze C, Alexandre N, Delmaire C, Méneret A, Depienne C, Poupon C, Hertz-Pannier L, Cincotta M, Vidailhet M, Lehericy S, Meunier S, Roze E. Gallea C, et al. Brain. 2013 Nov;136(Pt 11):3333-46. doi: 10.1093/brain/awt258. Epub 2013 Sep 20. Brain. 2013. PMID: 24056534

References

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    1. Descoteaux M, Deriche R, Knösche TR, Anwander A. Deterministic and probabilistic tractography based on complex fibre orientation distributions. IEEE Trans Med Imaging. 2009;28:269–82. - PubMed

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