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. 1989 Apr;27(1-2):83-5.
doi: 10.1007/BF02222205.

Effects of antihistamines on isolated human lung mast cells, basophil leucocytes and erythrocytes

H Y Lau  1 , F L Pearce
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Effects of antihistamines on isolated human lung mast cells, basophil leucocytes and erythrocytes

H Y Lau et al. Agents Actions. 1989 Apr.

Abstract

Low concentrations of H1- and H2-receptor directed compounds inhibited the immunologic secretion of histamine from human lung mast cells and basophil leucocytes and protected human erythrocytes from hypotonic lysis. Higher concentrations induced a release of the amine from the histaminocytes. These results are discussed in terms of the possible membrane effects of the test compounds.

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References

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