Developmental changes of serotonin and 5-hydroxyindoleacetic acid levels in specific regions of the pigeon central nervous system
- PMID: 2473856
- DOI: 10.1016/0165-3806(89)90099-0
Developmental changes of serotonin and 5-hydroxyindoleacetic acid levels in specific regions of the pigeon central nervous system
Abstract
Serotonin (5-HT) and 5-hydroxyindoleacetic acid (5-HIAA) levels were determined in the visual Wulst, optic lobes, retina, cerebellum and brainstem of the pigeon during embryonic and posthatching periods. 5-HT content increased during development in almost all regions. 5-HIAA content generally showed the highest values within the second posthatching week and then decreased to reach adult values. The high 5-HT turnover (as indicated by high (5-HIAA/5-HT ratio) observed over the first posthatching week suggests a possible role of 5-HT on developmental processes which occur in pigeon visual areas over the same time.
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