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Review
. 2014 May;15(5):327-39.
doi: 10.1038/nrm3786. Epub 2014 Apr 16.

Advances in whole-embryo imaging: a quantitative transition is underway

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Review

Advances in whole-embryo imaging: a quantitative transition is underway

Periklis Pantazis et al. Nat Rev Mol Cell Biol. 2014 May.

Abstract

With the advent of imaging probes and live microscopy, developmental biologists have markedly extended our understanding of the molecular and cellular details of embryonic development. To fully comprehend the complex mechanistic framework that forms the developing organism, quantitative studies with high fidelity in space and time are now required. We discuss how integrating established, newly introduced and future imaging tools with quantitative analysis will ensure that imaging can fulfil its promise to elucidate how new life begins.

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