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. 1989 Mar-Apr;10(2):369-74.
doi: 10.1016/0196-9781(89)90045-4.

Tissue-specific sex differences in galanin-like immunoreactivity and galanin mRNA during development in the rat

S M Gabriel  1 , L M Kaplan, J B Martin, J I Koenig
Affiliations

Tissue-specific sex differences in galanin-like immunoreactivity and galanin mRNA during development in the rat

S M Gabriel et al. Peptides. 1989 Mar-Apr.

Abstract

Galanin-like immunoreactivity (Gal-LI), as determined by radioimmunoassay, was detectable in the brain and gastrointestinal tract by day 15 of gestation. Concentrations of Gal-LI increased after birth in the hypothalamus but decreased in the stomach and duodenum. A sex difference in Gal-LI concentrations appeared during puberty in the median eminence, neurointermediate lobe, and the anterior pituitary (AP), where females had higher Gal-LI concentrations compared to males. This difference was most pronounced in the AP; adult females had up to 4-fold greater Gal-LI concentrations and 5-fold more abundant rGal-specific mRNA compared to males.

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