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Review
. 2014:2014:525913.
doi: 10.1155/2014/525913. Epub 2014 Jan 9.

Cell transfer therapy for cancer: past, present, and future

Xiaoling Qian  1 , Xian Wang  1 , Hongchuan Jin  1
Affiliations
Review

Cell transfer therapy for cancer: past, present, and future

Xiaoling Qian et al. J Immunol Res. 2014.

Abstract

Cell transfer therapy for cancer has made a rapid progress recently and the immunotherapy has been recognized as the fourth anticancer modality after operation, chemotherapy, and radiotherapy. Lymphocytes used for cell transfer therapy include dendritic cells, natural killer (NK) cells, and T lymphocytes such as tumor-infiltrating lymphocytes (TILs) and cytotoxic T lymphocytes (CTLs). In vitro activated or engineered immune cells can traffic to cancer tissues to elicit persistent antitumor immune response which is very important especially after immunosuppressive treatments such as chemotherapy. In this review, we overviewed recent advances in the exploration of dendritic cells, NK cells, and T cells for the treatment of human cancer cells.

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References

    1. Coley WB. The treatment of malignant tumors by repeated inoculations of erysipelas: with a report of ten original cases. Clinical Orthopaedics and Related Research. 1991;(262):3–11. - PubMed
    1. Coley WB. The treatment of inoperable sarcoma by bacterial toxins (the mixed toxins of the Streptococcus erysipelas and the Bacillus prodigiosus) Proceedings of the Royal Society of Medicine. 1910;3:1–48. - PMC - PubMed
    1. Lotze MT, Matory YL, Rayner AA. Clinical effects and toxicity of interleukin-2 in patients with cancer. Cancer. 1986;58(12):2764–2772. - PubMed
    1. Steinman RM, Cohn ZA. Pillars article: identification of a novel cell type in peripheral lymphoid organs of mice. I. Morphology, quantitation, tissue distribution. J. Exp. Med.1973. 137: 1142–1162. Journal of Immunology. 2007;178(1):5–25. - PubMed
    1. Palucka K, Banchereau J. Cancer immunotherapy via dendritic cells. Nature Reviews Cancer. 2012;12(4):265–277. - PMC - PubMed

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