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Review
. 2014 Mar;47(2):74-83.
doi: 10.3961/jpmph.2014.47.2.74. Epub 2014 Mar 31.

Environmental mercury and its toxic effects

Kevin M Rice  1 , Ernest M Walker Jr  2 , Miaozong Wu  1 , Chris Gillette  3 , Eric R Blough  4
Affiliations
Review

Environmental mercury and its toxic effects

Kevin M Rice et al. J Prev Med Public Health. 2014 Mar.

Abstract

Mercury exists naturally and as a man-made contaminant. The release of processed mercury can lead to a progressive increase in the amount of atmospheric mercury, which enters the atmospheric-soil-water distribution cycles where it can remain in circulation for years. Mercury poisoning is the result of exposure to mercury or mercury compounds resulting in various toxic effects depend on its chemical form and route of exposure. The major route of human exposure to methylmercury (MeHg) is largely through eating contaminated fish, seafood, and wildlife which have been exposed to mercury through ingestion of contaminated lower organisms. MeHg toxicity is associated with nervous system damage in adults and impaired neurological development in infants and children. Ingested mercury may undergo bioaccumulation leading to progressive increases in body burdens. This review addresses the systemic pathophysiology of individual organ systems associated with mercury poisoning. Mercury has profound cellular, cardiovascular, hematological, pulmonary, renal, immunological, neurological, endocrine, reproductive, and embryonic toxicological effects.

Keywords: Environment; Mercury; Toxicity.

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Conflict of interest statement

The authors have no conflicts of interest with the material presented in this paper.

Figures

Figure 1
Figure 1
Routes of mercury exposure in humans.
See this image and copyright information in PMC

References

    1. Clifton JC., 2nd Mercury exposure and public health. Pediatr Clin North Am. 2007;54(2):237–269. - PubMed
    1. US Department of Health and Human Services, Public Health Service. Toxicological profile for mercury. Atlanta: US Department of Health and Human Services; 1999. pp. 1–600.
    1. Rice GE, Ambrose RB, Jr, Bullock OR, Jr, Smawtout J. Mercury study report to Congress. Durham: US Environmental Protection Agency; 1997. pp. 1.1–6.30.
    1. Davidson PW, Myers GJ, Weiss B. Mercury exposure and child development outcomes. Pediatrics. 2004;113(4 Suppl):1023–1029. - PubMed
    1. Goldman LR, Shannon MW American Academy of Pediatrics: Committee on Environmental Health. Technical report: mercury in the environment: implications for pediatricians. Pediatrics. 2001;108(1):197–205. - PubMed

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