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. 2014:2014:745462.
doi: 10.1155/2014/745462. Epub 2014 Mar 16.

Oligodendroglioma arising in mature cystic teratoma

Betül Unal  1 , Faruk Güleç  2 , Murat Sedele  2
Affiliations

Oligodendroglioma arising in mature cystic teratoma

Betül Unal et al. Case Rep Oncol Med. 2014.

Abstract

Background. Development of neuroepithelial tumors from mature cystic teratoma is very rare. We present a case of oligodendroglioma developing inside mature cystic teratoma. Case. Eighteen-years-old female, right adnexal mass with solid and cystic areas was detected. Sections showed all three germ layers. Also, a tumoral lesion was observed in a glial fibrillary matrix. Tumor was composed of monotonous, uniform cells which have oval-round nucleus, perinuclear halo, and indistinct cytoplasm. GFAP, EGFR, P53 were positive. Conclusions. We diagnosed oligodendroglioma arising from mature cystic teratoma. There was no recurrence at the end of 13 months followup. The number of cases which have been reported in the literature is only a few.

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Figures

Figure 1
Figure 1
Tumoral lesion inside mature cystic teratoma with glial fibrillary matrix.
Figure 2
Figure 2
The sections showing a monotonous population of round, uniform cells with a hyperchromatic nucleus and perinuclear halo.
Figure 3
Figure 3
“Fried-egg” appearance of oligodendroglioma.
Figure 4
Figure 4
GFAP positivity in tumor cells.
See this image and copyright information in PMC

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