Microbial learning lessons: SFB educate the immune system
- PMID: 24745329
- DOI: 10.1016/j.immuni.2014.04.002
Microbial learning lessons: SFB educate the immune system
Abstract
Segmented filamentous bacteria (SFB) contribute to immune-system maturation. In this issue of Immunity, Goto et al. (2014) and Lécuyer et al. (2014) provide evidence for how SFB induce antigen-specific T helper 17 cells and promote development of adaptive immunity at discrete mucosal sites.
Copyright © 2014 Elsevier Inc. All rights reserved.
Comment on
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Segmented filamentous bacteria antigens presented by intestinal dendritic cells drive mucosal Th17 cell differentiation.Immunity. 2014 Apr 17;40(4):594-607. doi: 10.1016/j.immuni.2014.03.005. Epub 2014 Mar 27. Immunity. 2014. PMID: 24684957 Free PMC article.
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Segmented filamentous bacterium uses secondary and tertiary lymphoid tissues to induce gut IgA and specific T helper 17 cell responses.Immunity. 2014 Apr 17;40(4):608-20. doi: 10.1016/j.immuni.2014.03.009. Immunity. 2014. PMID: 24745335
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