Quantitation of HIV-1 activity in tissue culture supernatants: effects of culture condition on syncytial assays and virus production
- PMID: 2474561
- DOI: 10.1016/0166-0934(89)90008-6
Quantitation of HIV-1 activity in tissue culture supernatants: effects of culture condition on syncytial assays and virus production
Abstract
We have compared the infectivity titres, reverse transcriptase levels and antigen titres in the supernatants from persistently infected cell lines that produce a variety of HIV-1 isolates. We found a poor correlation between the different assays, and a variability in viral activity dependent on culture medium.
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