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Review
. 2014 Apr 24;10(4):e1004016.
doi: 10.1371/journal.ppat.1004016. eCollection 2014 Apr.

An overview of respiratory syncytial virus

Jia Meng  1 , Christopher C Stobart  1 , Anne L Hotard  1 , Martin L Moore  1
Affiliations
Review

An overview of respiratory syncytial virus

Jia Meng et al. PLoS Pathog. .
No abstract available

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Conflict of interest statement

MLM and Emory University are entitled to licensing fees derived from various agreements Emory has entered into non-exclusive licensing agreements related to some of the technologies described in this paper. The terms of this arrangement have been reviewed and approved by Emory University in accordance with its conflict of interest policies. This does not alter our adherence to all PLOS policies on sharing data and materials.

Figures

Figure 1
Figure 1. Conservation of RSV F protein antigenic sites characterized to date.
Four antigenic group A and three group B RSV F protein sequences were aligned using ClustalW and visualized with Geneious Pro software. The RSV A2 F (Genbank protein accession ACO83301) serves as the reference strain. The other representative strains are A/1998/12-21 (Nashville, Tennessee, US, accession AFM95385), A/RSV-12 (Denver, Colorado, US, 2004–2005, accession AEO45929), A/Riyadh/2009 (Riyadh, Saudi Arabia, accession AEO23052), B/9320 (Massachusetts, US, 1977, accession AAR14266), B/NH1276 (New Haven, Connecticut, US, 2002, accession AFD34264), and B/TX11-56 (Dallas, Texas, US, 2011, accession AFD34265). Positions of antigenic sites 0, I, II, and IV are from reference .
See this image and copyright information in PMC

References

    1. Zhou H, Thompson WW, Viboud CG, Ringholz CM, Cheng PY, et al. (2012) Hospitalizations associated with influenza and respiratory syncytial virus in the United States, 1993–2008. Clin Infect Dis 54: 1427–1436. - PMC - PubMed
    1. Hall CB, Weinberg GA, Iwane MK, Blumkin AK, Edwards KM, et al. (2009) The burden of respiratory syncytial virus infection in young children. N Engl J Med 360: 588–598. - PMC - PubMed
    1. Thompson WW, Shay DK, Weintraub E, Brammer L, Cox N, et al. (2003) Mortality associated with influenza and respiratory syncytial virus in the United States. JAMA 289: 179–186. - PubMed
    1. Nair H, Nokes DJ, Gessner BD, Dherani M, Madhi SA, et al. (2010) Global burden of acute lower respiratory infections due to respiratory syncytial virus in young children: a systematic review and meta-analysis. Lancet 375: 1545–1555. - PMC - PubMed
    1. Mahadevia PJ, Masaquel AS, Polak MJ, Weiner LB (2012) Cost utility of palivizumab prophylaxis among pre-term infants in the United States: a national policy perspective. J Med Econ 15: 987–996. - PubMed

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