(4S)-5'-Chloro-3,7,7-trimethyl-5,6,7,8-tetra-hydro-4H-spiro-[1,2-oxazolo[5,4-b]quinoline-4,3'-indole]-2',5-dione
- PMID: 24764888
- PMCID: PMC3998327
- DOI: 10.1107/S1600536814000191
(4S)-5'-Chloro-3,7,7-trimethyl-5,6,7,8-tetra-hydro-4H-spiro-[1,2-oxazolo[5,4-b]quinoline-4,3'-indole]-2',5-dione
Abstract
In the title compound, C20H18ClN3O3, the five- and six-membered heterocycles fused through a spiro C atom are inclined to each other at an angle of 87.4 (1)°. In the tricyclic ring system, the cyclo-hexene ring adopts an envelope conformation with the spiro atom as the flap. In the crystal, two sets of N-H⋯O hydrogen bonds link the mol-ecules into columns containing centrosymmetric R 2 (2)(7) ring motifs and propagating along the b-axis direction.
Figures
References
-
- Bernstein, J., Davis, R. E., Shimoni, L. & Chang, N.-L. (1995). Angew. Chem. Int. Ed. Engl. 34, 1555–1573.
-
- Bruker (2008). APEX2, SADABS and SAINT Bruker AXS Inc., Madison, Wisconsin, USA.
-
- Farrugia, L. J. (2012). J. Appl. Cryst. 45, 849–854.
-
- Padwa, A., Brodney, M. A., Liu, B., Satake, K. & Wu, T. (1999). J. Org. Chem. 64, 3595–3607. - PubMed
-
- Sheldrick, G. M. (2008). Acta Cryst. A64, 112–122. - PubMed
LinkOut - more resources
Full Text Sources
Other Literature Sources