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. 2014 Jan 31;70(Pt 2):o226-7.
doi: 10.1107/S1600536814001743. eCollection 2014 Feb 1.

3-[2-(4-Fluoro-phen-yl)-2-oxoeth-yl]-5,5-di-phenyl-imidazolidine-2,4-dione

Affiliations

3-[2-(4-Fluoro-phen-yl)-2-oxoeth-yl]-5,5-di-phenyl-imidazolidine-2,4-dione

Joel T Mague et al. Acta Crystallogr Sect E Struct Rep Online. .

Abstract

The title compound, C23H17FN2O3, crystallizes with two independent mol-ecules in the asymmetric unit. The mol-ecules are connected by pairs of N-H⋯O hydrogen bonds and have slightly different conformations, as indicated by the dihedral angles between the central imidazolidine-2,4-dione ring and its three substituents. In one mol-ecule, these are 60.56 (1) and 82.66 (9)° to the phenyl rings and 84.35 (16)° to the 2-(4-fluoro-phen-yl)-2-oxoethyl side chain. In the other mol-ecule, the corresponding angles are 66.35 (10), 84.94 (9) and 86.31 (16)°. In the crystal, weak C-H⋯O inter-actions leading to a three-dimensional supramolecular architecture.

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Figures

Fig. 1.
Fig. 1.
Perspective view of the asymmetric unit showing the intermolecular N—H···O hydrogen bonds as dotted lines. Displacement ellipsoids are drawn at the 50% probability level.
Fig. 2.
Fig. 2.
Packing diagram viewed along b with intermolecular N—H···O and C—H···O interactions shown as dotted lines.

References

    1. Bruker (2009). SAINT Bruker AXS Inc., Madison, Wisconsin, USA.
    1. Bruker (2010). APEX2 Bruker AXS Inc., Madison, Wisconsin, USA.
    1. Carmi, C., Cavazzoni, A., Zuliani, V., Lodola, A., Bordi, F., Plazzi, P. V., Alfieri, R. R., Petronini, P. G. & Mor, M. (2006). Bioorg. Med. Chem. Lett. 16, 4021–4025. - PubMed
    1. Ciechanowicz-Rutkowska, M., Kieć-Kononowicz, K., Howard, S. T., Lieberman, H. & Hursthouse, M. B. (1994). Acta Cryst. B50, 86–96. - PubMed
    1. Coquerel, G., Petit, M. N. & Robert, F. (1993). Acta Cryst. C49, 824–825.