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. 2014 Mar 11;6(Suppl 1):O9.
doi: 10.1186/1758-2946-6-S1-O9. eCollection 2014 Mar.

Development of cannabinoid receptor (CB 2 R) ligands for application in PET studies - where to attach the radiolabel?

Robert Günther  1 , Rareş Moldovan  1 , Corinna Lueg  2 , Winnie Deuther-Conrad  1 , Bernhard Wünsch  2 , Peter Brust  1
Affiliations

Development of cannabinoid receptor (CB 2 R) ligands for application in PET studies - where to attach the radiolabel?

Robert Günther et al. J Cheminform. .
No abstract available

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Figures

Figure 1
Figure 1
Compounds 1 and 2 fitted into the binding pocket of the CB2R receptor model.
See this image and copyright information in PMC

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References

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    1. Günther R, Brust P. Synergistic approach of structure- based and ligand-based drug design for the development of selective cannabinoid receptor ligands. J Cheminform. 2012;4(Suppl 1):P11. doi: 10.1186/1758-2946-4-S1-O11. - DOI
    1. Gerebtzoff G, Seelig A. In Silico Prediction of Blood-Brain Barrier Permeation Using the Calculated Molecular Cross-Sectional Area as Main Parameter. J Chem Inf Model. 2006;6:2638–2650. - PubMed

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