Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2014 Mar 11;6(Suppl 1):O9.
doi: 10.1186/1758-2946-6-S1-O9. eCollection 2014 Mar.

Development of cannabinoid receptor (CB 2 R) ligands for application in PET studies - where to attach the radiolabel?

Robert Günther  1 , Rareş Moldovan  1 , Corinna Lueg  2 , Winnie Deuther-Conrad  1 , Bernhard Wünsch  2 , Peter Brust  1
Affiliations

Development of cannabinoid receptor (CB 2 R) ligands for application in PET studies - where to attach the radiolabel?

Robert Günther et al. J Cheminform. .
No abstract available

PubMed Disclaimer

Figures

Figure 1
Figure 1
Compounds 1 and 2 fitted into the binding pocket of the CB2R receptor model.
See this image and copyright information in PMC

References

    1. Rühl T, Deuther-Conrad W, Fischer S, Günther R, Hennig L, Krautscheid L, Brust P. Cannabinoid Receptor Type 2 (CB2)-Selective N-Aryl-Oxadiazolyl-Propionamides: Synthesis, Radiolabelling, Molecular Modelling and Biological Evaluation. Org Med Chem Lett. 2012;2:32. doi: 10.1186/2191-2858-2-32. - DOI - PMC - PubMed
    1. Günther R, Brust P. Synergistic approach of structure- based and ligand-based drug design for the development of selective cannabinoid receptor ligands. J Cheminform. 2012;4(Suppl 1):P11. doi: 10.1186/1758-2946-4-S1-O11. - DOI
    1. Gerebtzoff G, Seelig A. In Silico Prediction of Blood-Brain Barrier Permeation Using the Calculated Molecular Cross-Sectional Area as Main Parameter. J Chem Inf Model. 2006;6:2638–2650. - PubMed

LinkOut - more resources