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Case Reports
. 2011 May 6;1(2):e34.
doi: 10.4081/cp.2011.e34. eCollection 2011 May 16.

Coexistence of Behçet's disease with ankylosing spondylitis and familial Mediterranean fever: a rare occurrence

Makram Frigui  1 , Manel Kechaou  1 , Moez Jallouli  1 , Neila Kaddour  1 , Habiba Bouhamed Chaabouni  2 , Zouhir Bahloul  1
Affiliations
Case Reports

Coexistence of Behçet's disease with ankylosing spondylitis and familial Mediterranean fever: a rare occurrence

Makram Frigui et al. Clin Pract. .

Abstract

Behçet's disease (BD) and familial Mediterranean fever (FMF), which are two separate diseases sharing some clinical features, may also coexist in the same patient. Further investigations are needed to understand whether this coexistence is due to either chance or geographical distribution patterns of these diseases or to common etiopathogenetic characteristics. Spondylarthritis as part of the clinical picture in these two diseases has been questioned and probably it is not a prominent characteristic of any of them. We report a 35-year-old Tunisian man who had an association of BD, FMF and Human Leukocyte Antigen (HLA) B27 positive ankylosing spondylitis. Although that spondylarthritis is an infrequent joint involvement of FMF and BD, it must be looked for in case of association of these diseases.

Keywords: Behçet’s disease; ankylosing spondylitis, MEFV gene.; familial Mediterranean fever.

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Conflict of interest statement

Conflict of interest: the authors report no conflicts of interest.

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