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Case Reports
. 2012 Apr 2;2(2):e41.
doi: 10.4081/cp.2012.e41. eCollection 2012 Mar 30.

Haematuria in association with Lynch syndrome

Marwan Ma'ayeh  1 , Richard Power  1 , Deirdre Mary Fanning  1
Affiliations
Case Reports

Haematuria in association with Lynch syndrome

Marwan Ma'ayeh et al. Clin Pract. .

Abstract

A 40-year-old Caucasian male presented to the Emergency Department complaining of intermittent painless frank haematuria. Past medical history was significant for Hereditary Non-Polyposis Colon Cancer (HNPCC) and a prophylactic total colectomy. Computed tomography urogram showed thickening in the posterior wall of the bladder. Cystoscopy showed a small bladder mass. Histology showed a papillary urothelial neoplasm of low malignant potential. HNPCC, also known as Lynch Syndrome, is an autosomal dominant disorder responsible for 3-5% of colorectal cancers. There are certain cancers known to be associated with HNPCC; colorectal cancer, endometrial, ovarian, stomach, pancreas, biliary tract, small bowel, brain, renal pelvic and ureteric tumours, sebaceous gland adenomas and keratocanthomas. An association with bladder tumours is not well established.

Keywords: colon cancer; hematuria; surgical oncology; urological cancer; urology..

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Conflict of interest statement

Conflict of interest: the authors declare no potential conflicts of interest.

Figures

Figure 1
Figure 1
Transverse section of computed tomography abdomen and pelvis showing thickening of the right aspect of the posterior bladder wall at the level of the seminal vesicles.
See this image and copyright information in PMC

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