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Case Reports
. 2014 Jun;18(3):295-7.
doi: 10.1016/j.jaapos.2014.01.007. Epub 2014 Apr 24.

Successful treatment of juvenile xanthogranuloma using bevacizumab

Noy Ashkenazy  1 , Christopher R Henry  2 , Ashkan M Abbey  3 , Craig A McKeown  1 , Audina M Berrocal  1 , Timothy G Murray  4
Affiliations
Case Reports

Successful treatment of juvenile xanthogranuloma using bevacizumab

Noy Ashkenazy et al. J AAPOS. 2014 Jun.

Abstract

Juvenile xanthogranuloma (JXG) is an uncommon non-Langerhans cell histiocytic disorder that occurs predominantly in infants. Traditional treatment of ocular JXG involves the administration of topical or local corticosteroids. We treated 2 children with JXG refractory to local corticosteroid therapy with off-label intraocular bevacizumab. To our knowledge, this is the first report of successful use of bevacizumab for ocular JXG.

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