Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2014 Mar-Apr;89(2):323-5.
doi: 10.1590/abd1806-4841.20142857.

Arthritis and diagnosis of leprosy: a case report and review of the literature

Affiliations
Review

Arthritis and diagnosis of leprosy: a case report and review of the literature

Tania Rita Moreno de Oliveira Fernandes et al. An Bras Dermatol. 2014 Mar-Apr.

Abstract

Leprosy is clinically characterized by involvement of peripheral nerves and skin. The immunological profile of the individual defines the diversity of clinical manifestations, from skin disorders to systemic manifestations, especially the articulation ones, common in multibacillary forms, which may mimic collagen diseases and often posing diagnostic difficulties in endemic areas. This is a case report of asymmetric polyarthritis of small and large articulations associated with skin lesions which had been treated by a rheumatologist for 2 years with initial clinical diagnosis of rheumatoid arthritis, and later, with the appearance of skin lesions, of systemic lupus erythematosus.

PubMed Disclaimer

Conflict of interest statement

Conflict of interest: None

Figures

FIGURE 1
FIGURE 1
Erythematous nodules on thighs. Hand with edema and erythema. Fifth finger in moving claw
FIGURE 2
FIGURE 2
Erythematous nodules on face
FIGURE 3
FIGURE 3
Edema on both feet
FIGURE 4
FIGURE 4
Intradermal smear with alcohol-acid resistant bacillus, single and in small groups
FIGURE 5
FIGURE 5
Edema regression on feet 2 months after start of treatment
FIGURE 6
FIGURE 6
Regression of lesions on face 2 months after treatment

Similar articles

Cited by

References

    1. Who.int . Prevalence of leprosy at start of 2011. [cited 2013 Apr 28]. [homepage on the Internet] Available from: http://www.who.int/lep/situation/prevalence/en/#.
    1. Prevedello FC, Távora MM. Leprosy: a genetic disease? An Bras Dermatol. 2007;82:451–459.
    1. Freitas D S, Machado N, Andrigueti FV, Reis ET, Neto, Pinheiro MM. Lepromatous leprosy associated with the use of anti-TNF α therapy: case report. Rev Bras Reumatol. 2010;50:333–339. - PubMed
    1. Ribeiro SLE, Guedes EL, Pereira HLA, Souza LS. Manifestações sistêmicas e ulcerações cutâneas da hanseníase: diagnóstico diferencial com outras doenças reumáticas. Rev Bras Reumatol. 2009;49:623–629.
    1. Freire M, Carneiro HE, Teodoro RB, Cecin HA. Manifestações Reumáticas na hanseníase: dificuldades no diagnóstico precoce. Rev Bras Reumatol. 1998;38:210–214.

LinkOut - more resources