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Case Reports
. 2014 Mar-Apr;89(2):351-2.
doi: 10.1590/abd1806-4841.20142621.

Chromoblastomycosis: an exuberant case

Affiliations
Case Reports

Chromoblastomycosis: an exuberant case

Nathália Matos Gomes et al. An Bras Dermatol. 2014 Mar-Apr.

Abstract

Chromoblastomycosis is a chronic subcutaneous mycotic infection caused by dematiaceous saprophytic moulds. The most frequently isolated agent is Fonsecae pedrosoi. This article reports a case of a man from the Amazon region in Northern Brazil who presented with a lesion of 12 months' duration, which gradually increased in size until covering the majority of his right leg. A successful treatment with itraconazole was performed.

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Conflict of interest statement

Conflict of interest: None

Figures

FIGURE 1
FIGURE 1
Extensive and polymorphic lesion: ulcers, verrucous plaques with dark stippled lines and fibrotic areas that caused even severe penile lymphedema.
FIGURE 2
FIGURE 2
(A) Dramatic response after using itraconazole 400mg/day for 15 days; (B) Response maintained after 5 months of continuous use of the drug. Focuses of active areas were detected, interspersed with extensive cicatricial fibrous tissue
FIGURE 3
FIGURE 3
Histophatological examination: pseudoepitheliomatous hyperplasia, dense mixed inflammatory infiltrate and presence of round, brownish, anucleate structures named fumagoid bodies
FIGURE 4
FIGURE 4
Mycological study: direct examination (a) and microculture chatacterizing Fonsecae pedrosoi

References

    1. Lupi O, Tyring SK, McGinnis MR. Tropical dermatology: Fungal tropical diseases. J Am Acad Dermatol. 2005;53:931–951. - PubMed
    1. Sotto MN, De Brito T, Silva AM, Vidal M, Castro LG. Antigen distribution and antigen- presenting cells in skin biopsies of human chromoblastomycosis. J Cutan Pathol. 3:14–18. - PubMed
    1. Queiroz-Telles F, Santos DWCL. Chromoblastomycosis in the Clinical Practice. Curr Fungal Infect Rep. 2012;6:312–319.
    1. López Martínez R, Méndez Tovar LJ. Chromoblastomycosis. Clin Dermatol. 2007;25:188–194. - PubMed
    1. Ricard-Blum S, Hartmann DJ, Esterre P. Monitoring of extracellular rmatrix metabolism and cross-linking in tissue, serum and urine of patients with chromoblastomycosis, a chronic skin fibrosis. Eur J Clin Invest. 1998;28:748–754. - PubMed

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