Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2014 Mar-Apr;89(2):357-8.
doi: 10.1590/abd1806-4841.20142696.

Case for diagnosis. Dermatofibrosarcoma protuberans

Joanna Pimenta de Araujo Franco  1 , Caroline Cruz Barbosa  1 , Bárbara Ferreira Saraiva da Fonseca  1 , Ricardo Barbosa Lima  1 , Antônio Macedo D'Acri  1 , Carlos José Martins  1
Affiliations
Case Reports

Case for diagnosis. Dermatofibrosarcoma protuberans

Joanna Pimenta de Araujo Franco et al. An Bras Dermatol. 2014 Mar-Apr.

Abstract

Dermatofibrosarcoma protuberans is a fibrohistiocytic tumor of intermediate malignancy with aggressive localized growth, high recurrence rate, but low metastatic potential. It appears as a hardened plaque, with slow growth, upon which the development of nodules occurs. It predominates in the trunk and is unusual in acral locations. Histopathology reveals spindle cells with storiform pattern and cartwheel-like or whirlwind-like aspect. Immunohistochemistry shows positivity for CD34. The treatment is surgical. We report a case of long evolution, with an unusual location, that relapsed after surgery, to emphasize the importance of early diagnosis and proper treatment, avoiding aggressive resections with increased morbidity.

PubMed Disclaimer

Conflict of interest statement

Conflict of interest: None

Figures

FIGURE 1
FIGURE 1
Irregular, nodular, indurate lesion with erythematous surface with teleangiectasias. A) Overview B) Lesion detail
FIGURE 2
FIGURE 2
A) proliferation of spindle cells, with storiform pattern and “cartwheel” aspect in the dermis. HE200x B) Immunohistochemistry with positivity for CD34
FIGURE 3
FIGURE 3
Post-operatory image showing amputation of the fourth left finger
See this image and copyright information in PMC

References

    1. Fleury LFF, Júnior, Sanches JA., Júnior Primary cutaneous sarcomas. An Bras Dermatol. 2006;81:207–221.
    1. Junqueira G, Júnior, Amaral RL, Espíndola BM, Pinto RD, Covatti E, Souza JA, et al. Dermatofibrossarcoma protuberans: relato de sete casos. An Bras Dermatol. 2006;81:207–221.
    1. Calonje E. Soft-tissue tumours and tumour-like conditions. In: Burns T, Breathnach S, Cox N, Griffiths C, editors. Rook's textbook of dermatology. Oxford: Blackwell Publishing; 2010. pp. 56–56.pp. 56.12–56.13.
    1. Kamino K, Meehan SA, Pui J. Proliferações fibrosas e fibro-histiocitóticas da pele e dos tendões. In: Bologna JL, Jorizzo JL, Rapini RP, editors. Dermatologia. 2 ed. trad. [Dermatology]. Rio de Janeiro: Elsevier; 2011. pp. 1813–1830.
    1. James WD, Berger TG, Elston DM. James WD, Berger TG, Elston DM. Andrews, Doenças da pele: dermatologia clínica. Skin diseases: clinical dermatology. 10 ed. trad. Rio de Janeiro: Elsevier; 2007. Tumores dérmicos e subcutâneos. Subcutaneous and dermic tumors; pp. 581–632.

Publication types

LinkOut - more resources