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Comment
. 2014 Apr 26;106(5):dju086.
doi: 10.1093/jnci/dju086.

Re: Role of the oxidative DNA damage repair gene OGG1 in colorectal tumorigenesis

Ben Kinnersley  1 , Stephan Buch  1 , Sergi Castellví-Bel  1 , Susan Mary Farrington  1 , Asta Forsti  1 , Jochen Hampe  1 , Kari Hemminki  1 , Robert M W Hofstra  1 , Emma Northwood  1 , Claire Palles  1 , Manuela Pinheiro  1 , Clara Ruiz-Ponte  1 , Clemens Schafmayer  1 , Manuel R Teixeira  1 , Helga Westers  1 , Tom van Wezel  1 , D Timothy Bishop  1 , Ian Tomlinson  1 , Malcolm G Dunlop  1 , Richard S Houlston  2
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Comment

Re: Role of the oxidative DNA damage repair gene OGG1 in colorectal tumorigenesis

Ben Kinnersley et al. J Natl Cancer Inst. .
No abstract available

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Figures

Figure 1.
Figure 1.
Forest plot of association between OGG1 c.923A and colorectal cancer risk. Studies were weighted according to the inverse of the variance of the log of the odds ratio (OR) calculated by unconditional logistic regression. Meta-analysis under a fixed-effects model was conducted using standard methods. Cochran’s Q statistic to test for heterogeneity and the I 2 statistic to quantify the proportion of the total variation due to heterogeneity were calculated. Horizontal lines indicate 95% confidence intervals (CIs). Boxes indicate odds ratio point estimate; its area is proportional to the weight of the study. Diamond (and broken line) indicates overall summary estimate, with confidence interval given by its width. Unbroken vertical line indicates null value (OR = 1.0). Risk allele frequencies are shown in square brackets.
See this image and copyright information in PMC

Comment in

  • Response.
    Smith CG, West H, Harris R, Idziaszczyk S, Maughan TS, Kaplan R, Richman S, Quirke P, Seymour M, Moskvina V, Steinke V, Propping P, Hes FJ, Wijnen J, Cheadle JP. Smith CG, et al. J Natl Cancer Inst. 2014 Apr 26;106(5):dju087. doi: 10.1093/jnci/dju087. J Natl Cancer Inst. 2014. PMID: 24771876 No abstract available.

Comment on

References

    1. Smith CG, West H, Harris R, et al. Role of the oxidative DNA damage repair gene OGG1 in colorectal tumorigenesis. J Natl Cancer Inst. 2013;105(16):1249–1253. - PubMed

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