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Review
. 2014 Apr 26;6(4):148-53.
doi: 10.4330/wjc.v6.i4.148.

Duration of dual antiplatelet treatment in the era of next generation drug-eluting stents

Seung-Woon Rha  1
Affiliations
Review

Duration of dual antiplatelet treatment in the era of next generation drug-eluting stents

Seung-Woon Rha. World J Cardiol. .

Abstract

Current percutaneous coronary intervention guidelines recommend dual antiplatelets (aspirin 100 mg + clopidogrel 75 mg daily) for at least 12 mo following drug-eluting stent (DES) implantation if patients are not at high risk of bleeding. Several reports have tried to shorten the dual antiplatelet therapy to 3-6 mo, especially following next-generation DES implantation, for cost-effectiveness. However, the clinical results are inconsistent and the data regarding next-generation DESs limited. In this report, recently published important pivotal reports regarding the optimal duration of dual antiplatelets following DES implantation are summarized.

Keywords: Drug-eluting stent; Dual antiplatelet treatment; Percutaneous coronary intervention.

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Figures

Figure 1
Figure 1
Landmark analyses of PRODIGY Trial[13]. Cumulative rates of composite of death, myocardial infarction or cerebrovascular accident in all recruited patients (A) or in patients randomly allocated to the drug-eluting stent groups (B) using the 6 mo landmark analysis.
See this image and copyright information in PMC

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