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. 2013:62:1-32.
doi: 10.1016/b978-0-12-800096-0.00001-9.

Myeloperoxidase in cardiovascular disease

Robert A Koeth, Virginia Haselden, W H Wilson Tang

Myeloperoxidase in cardiovascular disease

Robert A Koeth et al. Adv Clin Chem. 2013.

Abstract

Myeloperoxidase (MPO) plays a central role in the innate immune system by generating leukocyte-derived oxidants to combat invading pathogens. These reactive intermediates have been increasingly recognized to be potentially deleterious, causing oxidative injury in inflammatory disease states such as cardiovascular disease. Recent evidence now suggests that circulating MPO can act as a clinical prognostic indicator for patients with cardiovascular disease.

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