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. 2014 Mar;57(3):135-9.
doi: 10.3345/kjp.2014.57.3.135. Epub 2014 Mar 31.

Outcomes of chronic dialysis in Korean children with respect to survival rates and causes of death

Hye Jin Chang  1 , Kyoung Hee Han  2 , Min Hyun Cho  3 , Young Seo Park  4 , Hee Gyung Kang  1 , Hae Il Cheong  5 , Il Soo Ha  5
Affiliations

Outcomes of chronic dialysis in Korean children with respect to survival rates and causes of death

Hye Jin Chang et al. Korean J Pediatr. 2014 Mar.

Abstract

Purpose: Adult Korean patients on chronic dialysis have a 9-year survival rate of 50%, with cardiovascular problems being the most significant cause of death. The 2011 annual report of the North American Pediatric Renal Trials and Collaborative Studies group reported 3-year survival rates of 93.4% and relatively poorer survival in younger patients.

Methods: In this study, we have reviewed data from Korean Pediatric Chronic Kidney Disease Registry from 2002 to 2010 to assess survival rates and causes of death in Korean children on chronic dialysis.

Results: The overall estimated patient survival rates were 98.4%, 94.4%, and 92.1% at 1, 3, and 5 years, respectively. No significant difference was observed in survival rates between patients on peritoneal dialysis and those on hemodialysis. Patients for whom dialysis was initiated before 2 years of age (n=40) had significantly lower survival rates than those for whom dialysis was initiated at 6-11 years of age (n=140). In all, 26 patients had died; the mortality rate was 19.9 per 1,000 patient years. The most common causes of death were infections and comorbidities such as malignancy and central nervous system (CNS) or liver diseases.

Conclusion: The outcomes observed in this study were better than those observed in adults and comparable to those observed in pediatric studies in other countries. To improve the outcomes of children on chronic dialysis, it is necessary to prevent dialysis-related complications such as infection, congestive heart failure, or CNS hemorrhage and best control treatable comorbidities.

Keywords: Child; Dialysis; End-stage renal disease; Outcomes; Survival.

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Conflict of interest statement

No potential conflict of interest relevant to this article was reported.

Figures

Fig. 1
Fig. 1
Survival rate of Korean children on chronic dialysis. (A) Cumulative survival rate of all the patients; (B) cumulative survival rates of patients on different types of dialysis; (C) cumulative survival rates of patients in whom dialysis was initiated at different age groups.
See this image and copyright information in PMC

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