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Review
. 2014:2014:307268.
doi: 10.1155/2014/307268. Epub 2014 Mar 23.

Cryopreservation of embryos and oocytes in human assisted reproduction

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Review

Cryopreservation of embryos and oocytes in human assisted reproduction

János Konc et al. Biomed Res Int. 2014.

Abstract

Both sperm and embryo cryopreservation have become routine procedures in human assisted reproduction and oocyte cryopreservation is being introduced into clinical practice and is getting more and more widely used. Embryo cryopreservation has decreased the number of fresh embryo transfers and maximized the effectiveness of the IVF cycle. The data shows that women who had transfers of fresh and frozen embryos obtained 8% additional births by using their cryopreserved embryos. Oocyte cryopreservation offers more advantages compared to embryo freezing, such as fertility preservation in women at risk of losing fertility due to oncological treatment or chronic disease, egg donation, and postponing childbirth, and eliminates religious and/or other ethical, legal, and moral concerns of embryo freezing. In this review, the basic principles, methodology, and practical experiences as well as safety and other aspects concerning slow cooling and ultrarapid cooling (vitrification) of human embryos and oocytes are summarized.

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Figures

Figure 1
Figure 1
Increasing of average patient age in the last decade. Data are presented as mean ± SE.
Figure 2
Figure 2
Proportion of age groups at our clinic.

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