Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2014 Jun;174(6):999-1001.
doi: 10.1001/jamainternmed.2014.1179.

Use of mechanical ventilation by patients with and without dementia, 2001 through 2011

Tara Lagu  1 , Marya D Zilberberg  2 , Jennifer Tjia  3 , Penelope S Pekow  4 , Peter K Lindenauer  5
Affiliations

Use of mechanical ventilation by patients with and without dementia, 2001 through 2011

Tara Lagu et al. JAMA Intern Med. 2014 Jun.

Abstract

Increasing demand for US critical care resources, including beds, intensivists, and invasive mechanical ventilation (IMV),, has placed substantial strain on the critical care system. Since 2000, elderly patients treated in the intensive care unit have received higher intensity care (and have experienced lower mortality rates) than historical cohorts. Yet certain populations of elderly patients exposed to intensive care experience substantial long-term adverse effects, including functional decline and excess mortality. Patients with dementia receiving IMV, for example, are at high risk for delirium, which confers a 3.2-fold increased risk of 6-month mortality. The increasing use of aggressive therapies suggests that demand for IMV in elderly populations will increase in the future, both among patients that are likely to benefit and among those with terminal illness. We examined temporal trends in IMV use by older patients with and without dementia and projected future use.

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest Disclosures: None reported.

Figures

Figure
Figure. Projected Growth in Use of Invasive Mechanical Ventilation (IMV) by Patients 65 Years or Older With and Without Dementia
See this image and copyright information in PMC

References

    1. Wunsch H, Wagner J, Herlim M, Chong DH, Kramer AA, Halpern SD. ICU occupancy and mechanical ventilator use in the United States. Crit Care Med. 2013;41(12):2712–2719. - PMC - PubMed
    1. Stefan MS, Shieh MS, Pekow PS, et al. Epidemiology and outcomes of acute respiratory failure in the United States, 2001 to 2009: a national survey. J Hosp Med. 2013;8(2):76–82. - PMC - PubMed
    1. Lerolle N, Trinquart L, Bornstain C, et al. Increased intensity of treatment and decreased mortality in elderly patients in an intensive care unit over a decade. Crit Care Med. 2010;38(1):59–64. - PubMed
    1. Ely EW, Shintani A, Truman B, et al. Delirium as a predictor of mortality in mechanically ventilated patients in the intensive care unit. JAMA. 2004;291(14):1753–1762. - PubMed
    1. Zilberberg MD, de Wit M, Pirone JR, Shorr AF. Growth in adult prolonged acute mechanical ventilation: implications for healthcare delivery. Crit Care Med. 2008;36(5):1451–1455. - PubMed

Publication types