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Case Reports
. 2015 Feb;30(1):46-9.
doi: 10.1002/jca.21325. Epub 2014 Apr 30.

Successful management of thrombotic thrombocytopenic purpura in a Jehovah's Witness without plasma exchange

Wanxing Chai  1 , Abrar Chaudhry, Arthur P Rabinowitz
Affiliations
Case Reports

Successful management of thrombotic thrombocytopenic purpura in a Jehovah's Witness without plasma exchange

Wanxing Chai et al. J Clin Apher. 2015 Feb.

Abstract

Thrombotic thrombocytopenic purpura (TTP) is a hematologic emergency characterized by microangiopathic hemolytic anemia and thrombocytopenia. Plasma exchange is the standard treatment. Treating TTP without plasma exchange is a challenge. Due to religious beliefs, Jehovah's Witnesses do not accept transfusions of blood products. We report a case of successful treatment of TTP in a Jehovah's Witness using plasma exchange with albumin replacement.

Keywords: Jehovah's Witness; corticosteroid; plasma-free exchange; rituximab; thrombotic thrombocytopenic purpura.

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