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. 1989 Oct 15;45(10):996-8.
doi: 10.1007/BF01953060.

Further characterization of sulfated homopolysaccharides as anti-HIV agents

I Sugawara  1 , W Itoh, S Kimura, S Mori, K Shimada
Affiliations

Further characterization of sulfated homopolysaccharides as anti-HIV agents

I Sugawara et al. Experientia. .

Abstract

Fucoidan and dextran sulfate showed anti-HIV activities against mononuclear cells from AIDS patients, and they abrogated HIV reverse transcriptase (RT) activity by interacting with the HIV envelope in the membranes of target cells. Furthermore, they showed a synergistic effect with azidothymidine (AZT).

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References

    1. J Exp Med. 1986 Dec 1;164(6):2101-6 - PubMed
    1. J Immunol. 1982 Feb;128(2):621-4 - PubMed
    1. Immunobiology. 1982 Dec;163(5):527-38 - PubMed
    1. Cell Immunol. 1982 Apr;68(2):402-9 - PubMed
    1. Agents Actions. 1983 Jun;13(4):354-9 - PubMed

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