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Comment
. 2014 May;22(5):899-900.
doi: 10.1038/mt.2014.58.

The other face of chimeric antigen receptors

Gianpietro Dotti  1
Affiliations
Comment

The other face of chimeric antigen receptors

Gianpietro Dotti. Mol Ther. 2014 May.
No abstract available

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Figures

Figure 1
Figure 1
CAR function in (a) effector T cells to eliminate tumor cells and (b) nTregs to control autoimmune diseases. Costimulation in CAR-redirected nTregs remains to be defined. CAR, chimeric antigen receptor; MHC, major histocompatibility complex; nTregs, native T-regulatory cells; scFv, single-chain variable fragment; TCR, T-cell receptor.
See this image and copyright information in PMC

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References

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