Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Randomized Controlled Trial
. 2014 Oct;18 Suppl 5(0 5):S566-77.
doi: 10.1007/s10461-014-0786-z.

Tailored nutrition education and food assistance improve adherence to HIV antiretroviral therapy: evidence from Honduras

Homero Martinez  1 , Kartika Palar, Sebastian Linnemayr, Alexandria Smith, Kathryn Pitkin Derose, Blanca Ramírez, Hugo Farías, Glenn Wagner
Affiliations
Randomized Controlled Trial

Tailored nutrition education and food assistance improve adherence to HIV antiretroviral therapy: evidence from Honduras

Homero Martinez et al. AIDS Behav. 2014 Oct.

Abstract

Food insecurity and malnutrition negatively affect adherence to antiretroviral therapy (ART) and are associated with poor HIV clinical outcomes. We examined the effect of providing household food assistance and nutrition education on ART adherence. A 12-month prospective clinical trial compared the effect of a monthly household food basket (FB) plus nutrition education (NE) versus NE alone on ART adherence on 400 HIV patients at four clinics in Honduras. Participants had been receiving ART for an average of 3.7 years and were selected because they had suboptimal adherence. Primary outcome measures were missed clinic appointments, delayed prescription refills, and self-reported missed doses of ART. These three adherence measures improved for both groups over 12 months (p < 0.01), mostly within 6 months. On-time prescription refills improved for the FB plus NE group by 19.6 % more than the group receiving NE alone after 6 months (p < 0.01), with no further change at 12 months. Change in missed appointments and self-reported missed ART doses did not significantly differ by intervention group.

PubMed Disclaimer

Figures

Figure 1
Figure 1. Trends in adherence over 12 month follow-up, by measure of adherence and intervention group (Unadjusted)
a. Missed appointments in last 6 months (Center report) b. Delay in picking up ART (pharmacy report) c. Self-reported missed doses over the past month (patient report)
See this image and copyright information in PMC

References

    1. Deribe K, Hailekiros F, Biadgilign S, Amberbir A, Beyene B. Defaulters from antiretroviral treatment in Jimma University Specialized Hospital, Southwest Ethiopia. Trop Med Int Health. 2008 Mar;13(3):328–33. eng. - PubMed
    1. Franke M, Murray M, Muñoz M, et al. Food insufficiency is a risk factor for suboptimal antiretroviral therapy adherence among HIV-infected adults in urban Peru. AIDS Behav. 2011;15(7):1483–89. - PMC - PubMed
    1. Marcellin F, Boyer S, Protopopescu C, et al. Determinants of unplanned antiretroviral treatment interruptions among people living with HIV in Yaoundé, Cameroon (EVAL survey, ANRS 12–116) Trop Med Int Health. 2008 Dec;13(12):1470–8. eng. - PubMed
    1. Martin A, Palar K, Derose K, Adams J. Food insecurity and nutritional barriers to antiretroviral therapy: lessons from Latin America and the Caribbean. J HIV AIDS Soc Serv. 2011;10(2):194–214.
    1. Weiser S, Tuller D, Frongillo E, et al. Food Insecurity as a barrier to sustained antiretroviral therapy adherence in Uganda. PloS One. 2010;5(4):357–66. - PMC - PubMed

Publication types

Substances

LinkOut - more resources