Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2007;16(1):11-6.
doi: 10.1297/cpe.16.11. Epub 2007 Feb 7.

A case of primary hyperparathyroidism in childhood found by a chance hematuria

Yasuhisa Ohata  1 , Takehisa Yamamoto  1 , Yukihiro Kitai  1 , Yoshimi Mizoguchi  1 , Masaru Iwaki  1 , Kiyoaki Sumi  1 , Yasuhiro Fujikawa  1 , Minoru Koga  2 , Hideki Sugao  2 , Tsunesuke Shimotsuji  1 , Keiichi Ozono  3
Affiliations

A case of primary hyperparathyroidism in childhood found by a chance hematuria

Yasuhisa Ohata et al. Clin Pediatr Endocrinol. 2007.

Abstract

A 10-yr-old boy visited Minoh City Hospital complaining of gross hematuria. Laboratory investigations revealed hypercalcemia, hypophosphatemia, and elevated serum levels of parathyroid hormone. A stone was found in the right ureter with drip infusion pyelography. A parathyroid adenoma was successfully diagnosed with computed tomography, ultrasonography, and methoxy-2-isobutyl isonitrile (MIBI) scintigraphy. Multiple endocrine neoplasia was ruled out by normal results of endocrine laboratory examinations. Extracorporeal shock wave lithotripsy was performed to treat the urolithiasis, and the parathyroid adenoma was surgically removed. Primary hyperparathyroidism is rare in childhood; however, this case suggests that gross hematuria is an important sign of hyperparathyroidism.

Keywords: bone mineral density; calcium; hematuria; hyperparathyroidism; phosphate.

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
Cervical ultrasonography (transverse) showed a 15 × 10 × 3 mm low echoic lesion in the posterior part of the right thyroid gland.
Fig. 2
Fig. 2
Cervical CT showed a low-density nodule in the posterior part of the right thyroid gland without infiltration to surrounding organs.
Fig. 3
Fig. 3
MIBI scintigraphy showed a focus of MIBI accumulation in the right part of thyroid gland.
Fig. 4
Fig. 4
MIBI scintigraphy after surgery showed no MIBI accumulation.
See this image and copyright information in PMC

References

    1. Ito Y, Inoue D, Matsumoto T. Primary hyperparathyroidism. Nippon Rinsho 2001; 59(Suppl 8): 87–94(In Japanese) - PubMed
    1. Cupisti K, Raffel A, Dotzenrath C, Krousch M, Röher HD, Schulte KM. Primary hyperparathyroidism in the young age group: Particularities of diagnostic and therapeutic schemes. World Journal of Surgery 2004; 28: 1153–6 doi: 10.1007/s00268-004-7671-2 - DOI - PubMed
    1. Rapaport D, Ziv Y, Rubin M, Huminer D, Dintsuman M. Primary hyperparathyroidism in children. Journal of Pediatric Surgery 1986; 21: 395–7 doi: 10.1016/S0022-3468(86)80505-X - DOI - PubMed
    1. Cronin CS, Reeve TS, Robinson B, Clifton-Blight P, Guinea A, Delbredge L. Primary hyperparathyroidism in childhood and adolescence. J Paediatr Child Health 1996; 32: 397–9 doi: 10.1111/j.1440-1754.1996.tb00937.x - DOI - PubMed
    1. Greenbaum LA. Pathophysiology of body fluids and fluid therapy, Electrolyte and acid-base disorder. In: Behrman RE, Kliegman RM, et al., editors. Nelson textbook of pediatrics, 17th ed. Elsevier; 2004. p.215.