Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2014 Mar;36(2):162-4.
doi: 10.5581/1516-8484.20140035.

Improvement of thrombocytopenia after treatment for Helicobacter pylori in a patient with immunologic thrombocytopenic purpura

Aline Maia Rocha  1 , Luís Fábio Barbosa Botelho  1 , David Maia Rocha  2
Affiliations

Improvement of thrombocytopenia after treatment for Helicobacter pylori in a patient with immunologic thrombocytopenic purpura

Aline Maia Rocha et al. Rev Bras Hematol Hemoter. 2014 Mar.

Abstract

Immune thrombocytopenic purpura is the most common autoimmune hematologic disease, affecting individuals of different ages. Recently, the bacterium Helicobacter pylori entered the list of causes of immune thrombocytopenic purpura. Here we present the case of a 55-year-old female patient with low platelet counts initially attributed to chronic vaginal bleeding. As corticosteroid therapy was ineffective she was treated for H. pylori infection. Within four weeks the patient had a platelet count of 87.17 ×10(9)/L accompanied by clinical improvement of the symptoms.

Keywords: Causes; Helicobacter pylori; Immune thrombocytopenic purpura; Platelet count.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Mean platelet count response to the eradication of Helicobacter pylori bacteria. The treatment to eradicate H. pylori was carried out in June 2012, and, from then on, there was a great increase in the platelet count.
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

References

    1. Ahn Y.S. Triple play of H pylori in ITP. Blood. 2010;115:4155–4156. - PubMed
    1. Emilia G., Luppi M., Zucchini P., Morselli M., Potenza L., Forghieri F. Helicobacter pylori infection and chronic immune thrombocytopenic purpura: long-term results of bacterium eradication and association with bacterium virulence profiles. Blood. 2007;110:3833–3841. - PubMed
    1. Stasi R., Sarpatwari A., Segal J.B., Osborn J., Evangelista M.L., Cooper N. Effects of eradication of Helicobacter pylori infection in patients with immune thrombocytopenic purpura: a systematic review. Blood. 2009;113:1231–1240. - PubMed
    1. Stasi R., Provan D. Helicobacter pylori and Chronic ITP. ASH Education Book. 2008;206:11. - PubMed
    1. Semple J.W., Aslam R., Kim M., Speck E.R., Freedman J. Platelet-bound lipopolysaccharide enhances Fc receptor-mediated phagocytosis of IgG-opsonized platelets. Blood. 2007;109:4803–4805. - PubMed

LinkOut - more resources