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Review
. 2014 Mar;6(1):106-12.
doi: 10.5114/jcb.2014.42028. Epub 2014 Apr 3.

Primary brachytherapy as a radical treatment for endometrial carcinoma

Elzbieta van der Steen-Banasik  1
Affiliations
Review

Primary brachytherapy as a radical treatment for endometrial carcinoma

Elzbieta van der Steen-Banasik. J Contemp Brachytherapy. 2014 Mar.

Abstract

Surgery is the primary treatment for endometrial cancer, with radiation therapy having an established place in the adjuvant treatment setting. However, there is a population of patients with endometrial cancer who may not be suitable for surgery and primary radiation therapy as a treatment option. This article describes the place of radiotherapy in the management of endometrial cancer and describes the author's own experiences with primary brachytherapy in those patients who are unsuitable for surgery.

Keywords: HDR; brachytherapy; endometrial cancer.

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Figures

Fig. 1
Fig. 1
A methodology for the planning procedure including specification and optimization points. The dose specification points are at a point 2 cm from the central axis at the midpoint along the uterine applicator. Additional optimization points are placed at 2 cm from the central axis of the tandem at its midpoint. The isodose is widened at the uterine fundus to account for the increased uterine width at the fundus
Fig. 2
Fig. 2
A) CT-scan with Rotte applicator in the coronal view: The green and red points in the applicator are possible source positions. B) Contouring in the coronal view. The blue, pink, purple, and yellow contour lines are uterus, bowel, sigmoid, and urinary bladder, respectively. C) Definitive isodose distribution in the coronal view. The red isodose line illustrates 100%
Fig. 3
Fig. 3
A) CT scan with Rotte applicator in the sagittal view. The green and red points in the applicator are possible source positions. B) Contouring in the sagittal view. The blue, pink, purple, and yellow contour lines are uterus, bowel, sigmoid, and urinary bladder, respectively. C) Definitive isodose distribution in the sagittal view. The red isodose line illustrates 100%
Fig. 4
Fig. 4
A) CT scan with Rotte applicator in the transversal view. B) Contouring in the transversal view. The blue, pink, purple, and yellow contour lines are uterus, bowel, sigmoid and urinary bladder respectively. C) Definitive isodose distribution in the transversal view. The red isodose line illustrates 100%
See this image and copyright information in PMC

References

    1. http://www.cancerresearchuk.org/cancer-help/type/womb; accessed March 2014.
    1. Austin H, Austin JM, Jr, Patridge EE, et al. Endometrial cancer, obesity and body fat distribution. Cancer Res. 1991;51:568–572. - PubMed
    1. http://www.cijfersoverkanker.nl/; accessed May 2014.
    1. Benedetti PP, Basile S, Maneschi F, et al. Systematic pelvic lymphadenectomy vs. no lymphadenectomy in early stage endometrial carcinoma: randomized clinical trial. J Natl Cancer Inst. 2008;100:1707–1716. - PubMed
    1. Kitchener H, Swart AM, Qian Q, et al. Efficacy of systematic pelvic lymphadenectomy in endometrial cancer (MRC ASTEC trial): a randomized study. Lancet. 2009;373:125–136. - PMC - PubMed

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